Gallery of Dr. Dipnarine Maharaj MD FACP Appearance at the Dr. Oz WPBF Wellness Festival

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Dr. Dipnarine Maharaj Discusses Adult Stem Cell Breakthroughs in Parkinson’s

Dipnarine Maharaj

Dipnarine Maharaj during the apheresis process

The South Florida Bone Marrow Stem Cell Transplant Institute, under the direction of Medical Director and this Clinical Trial Principal Investigator, Dipnarine Maharaj MD, FACP, is studying the neuroprotective effects of granulocyte colony-stimulating factor (G-CSF) in several neurological disease models including Parkinson’s disease (PD).  The present study is an extension of his previously published work which reported on the therapeutic effect of G-CSF after the 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP) model of PD in mice was established.

Based on the mouse model, he found that G-CSF treatment markedly increased the number of dopaminergic neurons in the substantia nigra pars compacta (SNpc) of the G-CSF-treated group. Consistent with this finding, he found a significant increase in dopamine release under high K+ stimulation in the striatum of the G-CSF-treated animals compared to the MPTP-exposed mice.

Finally, he observed a persistent recovery of locomotor function in the G-CSF-treated animals. These results suggest the potential therapeutic value of G-CSF in treating PD, which he wishes to study further on humans with funding.

 

Dipnarine Maharaj Introduction to Adult Stem Cells

 

 

Dipnarine Maharaj Introduction to Adult Stem Cells

Dipnarine Maharaj

Dipnarine Maharaj – Medical Director, South Florida Bone Marrow Stem Cell Transplant Institute Boynton Beach, FL

INTRODUCTION
Stem cells have the power and potential to be one of the most effective agents against aging available to medicine today. A stem cell is an unspecified cell that can both self-renew (produce an exact clone of itself) and differentiate into mature tissues, such as the heart, lung, liver, etc. Adult stem cells are collected from bone marrow (bone marrow stem cells), peripheral blood (peripheral blood stem cells), and cord blood (cord blood stem cells). Embryonic stem cells are collected from a fertilized egg or from an embryo, and can form any of the 200 different tissue types present in the body. It is important to remember that embryonic stem cells are a foreign tissue, and thus carry the risk of all the complications associated with an allogeneic or an unrelated donor transplant if these cells are transplanted into an individual. This paper is concerned with adult stem cells.

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Cord Blood Banking Benefits – By Dr. Dipnarine Maharaj MD

Palm Beach Parkinson's Disease and Cancer Specialist Dr. Dipnarine Maharaj M.D.

Dr. Dipnarine Maharaj M.D. FACP, Adult Stem Cell and Cord Blood Banking Specialist

Storing your baby’s cord blood is one of the easiest things that new parents can do to protect their child’s health.  By storing the cord blood, parents can ensure that their child has a resource should they ever contract or develop a major illness.  With the advances of modern medicine the uses of cord blood stem cells is growing at a rapid pace.  Already cord blood banking can be used for:

Cancer

  • Acute Leukemia
  • Chronic Leukemia
  • High-Risk Solid Tumors
  • Hodgkin & Non-Hodgkin Lymphoma
  • Myelodysplastic Syndromes

Blood Disorders

Immune Disorders

Metabolic Disorders

  • Krabbe Disease
  • Hurler Syndrome
  • Metachromatic Leukodystrophy
  • Sanfilippo Syndrome

For the most part Cord Blood is discussed, however, most people don’t know that the Cord Tissue can also be saved and is a viable source of cord blood stem cells.  During this July of Cord Blood Awareness month, we should all be looking at ways that we can provide a bio-insurance for ourselves and Cord Blood Banking for your newborn baby is a great way to do that.

Dr. Dipnarine Maharaj M.D.  is the Medical Director of the Stem Cell Cryobank , an Adult Stem Cell and Cord Blood Bank, as well as the Medical Director of the South Florida Bone Marrow Stem Cell Transplant Institute.

Dr. Dipnarine Maharaj MD FACP – Welcome to My WordPress Site for Adult Stem Cells

Dr. Dipnarine Maharaj MD FACP – Welcome to My WordPress Site for Adult Stem Cells

 

WaddellsWhy bank adult stem cells?

In banking your own healthy adult stem cells, you will not need to depend on finding a matched donor.

1 in 200 people will need a stem cell transplant for a blood disorder during their lifetime. High dose chemotherapy followed by stem cell reinfusion has been the standard of care for many hematological disorders for decades. However, 70% of patients in need of a transplant do not have a matching donor or umbilical cord blood unit. (National Marrow Donor Registry, 2012). The best time to collect your adult stem cells is when you are healthy. A healthy immune system is the most important factor when it comes to longevity and the ability to fight off diseases. As you age, so do your stem cells, resulting in a steady decline in your stem cells’ efficacy, efficiency, and population. The time to collect and store your stem cells is NOW.

How can stem cells help you and your family

Although stem cell therapies currently only treat a few types of diseases due to the specialized nature of adult stem cells, the success of these established therapies, such as skin and blood transplants, provides hope that stem cells will be able to provide therapy for many diseases in the future that were previously thought to have no cure. Current treatment methods of many diseases involve simply alleviating symptoms, rather than curing the disease itself. Stem cells propose the possibility of re-growing the damaged cells, and then, being implanted in patients to replace damaged cells, ultimately curing the patient completely.

Blood and bone marrow stem cells, called hematopoietic cells, have been used for decades to treat leukemiassickle cell anemia, damaged bone marrow, and certain metabolic disorders and immunodeficiencies. Hematopoietic stem cells produce all types of blood cells, and preliminary tests have shown that these stem cells may also be able to give rise to other cell types besides blood cells.

The number of medical achievements stem cells have given rise to is growing at a rapid pace. Based on evolving research in regenerative medicine, we believe that the autologous (your own) stem cells will be used in the future to treat many diseases for which there are currently no cures. Having your stem cells collected today ensures that if they can be used to reverse any of these diseases you may develop, you are well prepared.