Do Cinderella Cells Hold The Key to Spinal Regeneration?

Do Cinderella Cells Hold The Key to Spinal Regeneration?
For millions who are suffering with spinal cord injuries, the storybook ball seems like fable from a land far away. Many have dreamed of a day where they can walk, dance, and run just like they are supposed to.  Everyone from infants all the way to seniors are affected by spinal cord disorders that have robbed them of their quality of life.  Despite the odds, they wish for better days and ultimately a cure.
Cinderella had her chance to go to the ball and live happily ever after.  Now scientists University of Edinburgh’s Medical Research Council (MRC) have isolated “Cinderella Cells” which have produced spinal cord, muscle, and bone tissue in the growing embryo.  Developments of these lab grown human tissues are giving hope for those suffering from neuromuscular conditions such as muscular dystrophy, spinal muscular atrophy and other motor neuron diseases, as this may one day serve as a viable treatment method. (For More Information on Breakthroughs like this, CLICK HERE)

 

 


The spinal cord houses the core components of the central nervous system, one of the most complex and highly organized structured systems within the body. The spinal cord is made from part of the neural tube during embryonic development. As the neural tube begins to develop, the notochord begins to secrete a factor known as ‘Sonic Hedgehog’ or SHH.  This induces the development of multipotent neural crest progenitors. As a result, the spinal cord, muscle and skeleton all form from a group of “Cinderella Cells” called Neuro-Mesodermal Progenitors (NMP). It is here, where scientists at the University of Edinburgh focused their research.

Over the years, researchers have been able to differentiate cells into liver, heart, muscle, skin, nerve, bone cells, and brain tissue from stem cells in the laboratory; however these NMP “Cinderella cells”, have eluded researchers for over a century.

The team at the medical research council still believes the goal of using lab-grown spinal cord tissue to treat debilitating neuromuscular conditions is still many years away. The hope is that stem cells transformed through this natural development process will resemble those that occur naturally in the body increasing the likelihood that transplants will integrate in patients.
It is advances like this that are laying the framework for future innovations and enabling scientists to treat diseases with stem cells. Stem cells are offering clues to the cellular causes of certain diseases and it is now up to future studies to piece those clues together.  (Learn more about Stem Cells by CLICKING HERE or Read Below)

HHS Identifies the “Next Evolution of Medical Treatments”

Healthcare is experiencing a growing crisis as conventional treatments reach their limitations and the United States develops an ever growing aging population. In this medical environment new and alternative strategies are needed. Stem cell based therapies are being evaluated for the treatment of a wide range of disorders. It is estimated that 132 million individuals in the United States alone may benefit from stem cell based therapy with the largest impact on patients with cancer, diabetes, autoimmune, cardiovascular and neurological disorders. Other patients likely to benefit include those with osteoporosis, severe burns, and spinal cord injuries. The U.S. Department of Health and Human Services has identified regenerative medicine as the “next evolution of medical treatments.”

The world’s first advanced stem cell education program was created to fill the growing need for knowledge on stem cells and regenerative medicine amongst physicians and healthcare professionals. This comprehensive program is guided by regenerative medicine pioneer and stem cell expert Dr. Dipnarine Maharaj and features instruction from the top scientists & physicians practicing in the field.

The Advanced Stem Cell Education Program (ASTEP) contains over 150 hours of lectures and video content designed to give you the most comprehensive understanding of this incredible aspect of medicine currently available. However, if you wish to target your education to areas of specific interests, you can select from one of the six subspecialty courses offered. Each subspecialty course contains lectures that cover the general biology of stem cells and the regulations of stem cell therapies to ensure proper understanding the course material.

In addition to the immense content included in the A-STEP program and its subspecialty courses, we offer a unique opportunity to learn about the practical applications of stem cells in the field of regenerative medicine. This practical module includes fifteen application-based lectures from leading stem cell physicians, practical demonstrations, and distinct stem cell preceptorship with Dr. Dipnarine Maharaj.
To find out more about the Advanced Stem Cell Education Program, CLICK HERE, or email education@bmscti.org

 

 

P.S. – ASTEP currently features both online modules and an in-person preceptorship.  For more information please click here for our information request form.

Related Links: 

FOX News WSVN Miami Story on New Stem Cell Protocol for Scleroderma 

Would you like to refer a patient to Dr. Maharaj?  Please use ourpatient referral form

Dr. Maharaj Featured on CNN Money for Adult Stem Cell BankingCLICK HERE.

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For more information on Saving Your Immune System, please see our informational brochure 

Attention all physicians – The Stem Cell Network is here – For More information click here
To learn more about Dr. Maharaj, the physician’s network, or about the latest protocols for diseases like cancer, Parkinson’s, diabetes, and more please contact the office at:

International: +1 (561) 752-5522

Email: info@bmscti.org

What Breast Cancer Survivors Need to Know About Stem Cells

What Breast Cancer Survivors Need to Know About Stem Cells

By Dr. Dipnarine Maharaj M.D.

 

The fight against breast cancer is a winnable fight. With modern advances in treatment, increased awareness, and early detection, the survival rate for women diagnosed with breast cancer is on the rise.

According to the American Cancer Society, women diagnosed with stage 1 breast cancer have a 100% survival rate. Even stage 3 cancer has a 72% survival rate over a period of 5 years. From all indications, it seems that we are winning the fight against breast cancer.

Life after Breast Cancer. What happens after you beat breast cancer? Ask any breast cancer survivor and you’ll immediate find out that nothing is ever the same. Ask a breast cancer survivor who has lived over 20 years post-diagnosis, and you’ll learn that total lifestyle change is required. Reckless choices such as eating a poor diet, not exercising, and excessive stress damage the body that the immune system in a way that the body can no longer take.

The Dangers of Recurrence. Even more alarming is the risk of recurrence, not of breast cancer, but of other types of cancer, most notably leukemia. Studies analyzing SEER data, patients who receive chemotherapy and radiation have an increased risk for cancers such as:

  • Myelodysplastic Syndrome (MDS)
  • Acute Myeloid Leukemia (AML)

During breast cancer treatment, the bone marrow is affected with chemotherapy and radiation, causing significant damage to the immune system. While good diet and exercise are steps that everyone can take, often a patient’s damaged immune system allows diseases like AML and MDS to proliferate.

Overall, the risk of developing leukemia post-chemotherapy amongst breast cancer patients is anywhere between 8-17%. In women aged 20-49, the risk of MDS was 30 times that of the normal population.

This is quite alarming because younger people would expect longer survival periods and a higher quality of life. Yet in younger people, we are seeing higher rates of MDS than even people who are in the 65-74+ age brackets.

The Robin Roberts Effect. This is exactly what happened to Robin Roberts, the beloved news anchor from ABC’s Good Morning America. In August of 2007, at the age of 46, she was diagnosed with breast cancer and immediately had surgery. By January of 2008 she had completed eight chemotherapy treatments, followed by more than six weeks of radiation treatment.

Four years later, she was diagnosed with Myelodysplastic Syndrome (MDS), a form of leukemia. Her personal battle brought the risk of cancer recurrence to millions and a public will to effectuate change. Be the Match Registry, a nonprofit organization run by the National Marrow Donor Program, experienced a 1,800% spike in donors the day Roberts went public with her illness.

Difficulty Finding a Match. However, those donors for the National Marrow Donor Program would not necessarily be able to access their own cells should they need a stem cell transplant for a blood cancer like MDS. Many times patients with cancer are not able to find an unrelated matching donor from the national donor program (your own cells are always a 100% match for you). Factors such as race and ethnicity play huge roles in determining the eligible donor pool for a particular patient. Minorities are historically underrepresented when it comes to the National Marrow Donor Program.

The Proactive Stem Cell Approach. As breast cancer survivors become more educated on these risks, many are opting to privately collect and store their own healthy adult stem cells post-chemotherapy and radiation, and not rely on potentially finding a donor if their cancer recurs. The idea behind this strategy is that the adult stem cells form the basis of the immune system. When cancer recurs, typically patients have seen their immune function decrease, with markers such as Natural Killer Cell function taking significant drops.

Natural Killer Cells are cells within the immune system that are responsible for killing cancers and other tumors within in the body. As the function of Natural Killer Cells increase, the body’s ability to defend itself against cancers rises as well.

Studies have shown that patients who have received autologous stem cell transplants have improved patient outcomes, faster recovery times, and better long term disease free survival, compared to patients who have undergone chemotherapy and radiation alone.

Having your adult stem cells in the bank is a safety net for breast cancer survivors. If a patient were to ever be diagnosed with a leukemia or a blood cancer, their banked adult stem cells would a powerful tool in the fight against cancer.

Currently the cost of this type of procedure can vary between $15,000-$45,000. For the most part, these procedures are not covered by Medicare or private insurance. As more patients decide to take these types of proactive steps for their health, the cost is anticipated to drop. However, don’t let the cost of the procedure convince you into waiting to collect and store your stem cells.

The Value of the Immune System. As we age our immune system gradually weakens over time. Starting around the age of 30 our immune systems are in a slow gradual decline until somewhere between the ages of 65-74. At that point, our immune system takes a significant drop. In essence, the longer you wait to collect and store your adult stem cells the weaker your immune system will be.

In addition to collecting and storing your stem cells, breast cancer patients should also monitor their immune systems on an annual basis. While many blood tests such as a CBC may turn up normal, there are abnormalities within the immune system that do not show up on regular diagnostic tests. Tracking the immune system gives a great indicator as to the body’s ability to fight cancer and other diseases.

BRCA1 and BRCA2 Risk. Females who have the BRCA1 and the BRCA2 gene for breast cancer, like Angelina Jolie, also fall into the category of those who need to have their immune system checked annually. While the presence of the gene indicates an increased risk for breast cancer, the mere presence of the gene doesn’t guarantee that you will get breast cancer. That’s why it is so important to monitor the immune system. If an abnormality within the immune system presents itself, it can be dealt with early before the spread of a cancer. While some females are opting for invasive mastectomy surgery, like Angelina Jolie, others are choosing to monitor their immune system before taking such drastic action.

Stem Cell Uses. As the benefits for stem cell therapy evolves, so will the amount of uses that are available for your banked adult stem cells. With over 2,000 U.S. Clinical Trials using adult stem cell therapies, there is clear evidence to show that an individual’s own stem cells have a significant capability for growth, repair, and regeneration of damaged tissue and cells in the body. Currently there are more than 70 accepted uses for adult stem cells including the treatment of many blood cancers, bone marrow failures, and immune disorders. For breast cancer patients, the risks are not just from the recurrence of breast cancer itself. With an impaired immune system, female breast cancer survivors are at an elevated risk for other types of cancer and illnesses. That’s why all breast cancer survivors should seriously consider banking and storing their healthy adult stem cells before it is too late.

 

 

Dr. Dipnarine Maharaj Delivers Keynote Address to CAM for Cancer Conference

Dr. Dipnarine Maharaj Delivers Keynote Address to CAM for Cancer Conference

On March 8 2014, Dr. Dipnarine Maharaj delivered the keynote address for the Annie Appleseed conference in West Palm Beach, FL. The conference featured leading speakers from North America on common and alternative modalities for cancer treatment.

Dipnarine Maharaj Keynote Address CAM For Cancer

Dipnarine Maharaj Keynote Address CAM For Cancer
This past weekend, stem cell transplant physician, Dr. Dipnarine Maharaj MD delivered the keynote address at the CAM for Cancer Conference hosted by the Annie Appleseed Project Foundation.  Dr. Maharaj lectured on adult stem cells and the advancements that are being made in cancer treatment.The conference was attended by over 200 participants and exhibitors who came from all over the world to hear top presenters like Dr. Maharaj share his stem cell cancer findings.

During his presentation, Dr. Maharaj shared evidence based information along with clinical studies to educate everyone from the most experienced physicians to the health and wellness minded individual.
“I want to thank Ann Fonfa for organizing an excellent conference,” stated Dr. Dipnarine Maharaj, founder of the South Florida Bone Marrow/Stem Cell Transplant Institute.  “I hope that everyone from the patients to the physicians were able to take away a new piece of information that they didn’t know before.  I always learn from my peers at these types of conferences and they serve a valuable purpose.”
The Annie Appleseed Project began as Ann Fonfa’s personal answers to questions (http://www.youtube.com/watch?v=NAAHa5zDsUI) (video) on natural(CAM) therapies, it has become a nationally recognized organization, and is now a nonprofit corporation in the state of Florida. (May 23, 2003)and tax exempt, 501 (c)3 as of August, 2003. From its inception the Annie Appleseed Project decided to Challenge the Existing treatment paradigm, to Question the existing research methods and subjects, and to Propose new directions for both ending with true Integrative Oncology.
Dr. Dipnarine Maharaj MD is one of America’s leading experts on adult stem cells and cancer treatment.  He has published extensively on bone marrow/stem cell transplants and peripheral blood stem cell collection in revered publications such as the Lancet, and Blood. Dr. Maharaj has also pioneered new protocols for Parkinson’s disease, neurological illnesses, and diabetes.  He was part of the pioneering group in Scotland that developed stem cell transplants for blood cancer patients.  Dr. Dipnarine Maharaj is currently running an FDA approved Phase I/II Clinical Trial for Solid Tumor Cancer Patients.

Stem Cell Webinar This Wednesday March 14 with Dr. Dipnarine Maharaj MD

 

 

Learn The Latest in Stem Cell Therapies For Your Patients

Join physicians from around the world in this unique webinar

Each year it seems that our patients are more at risk than ever for life threatening and chronic illness.  Whether it is the rapid growth of diabetes, Parkinson’s disease, or cancer, it seems that traditional medicine has had a difficult time keeping up.

Yet for over 40 years, stem cell transplants have been helping patients survive with quality of life in the face of some of the most dangerous of illnesses.  Physicians who want to do everything they can for their patients are now turning to the proven science of adult stem cell therapeutics.

Today patients with a wide range of diseases are being helped by adult stem cell protocols.  With over 2000 ongoing FDA clinical trials, the potential to expand the field and help patients is tremendous.

Join me for this unique webinar that will discuss some of the latest breakthroughs in patient care utilizing stem cell therapeutics.  We will discuss illnesses such as chronic fatigue syndrome, Alzheimer’s disease, type 1 and type 2 diabetes, fibromyalgia, ALS, cardiac disease, cancer, and much more.

Join me in this special presentation to spread the message of adult stem cells to help patients from around the world:

What: Stem Cell Network Physicians Webinar



When: March 12, 2014



Where: Online – Click Here to Register or paste link below into your browser 

http://stemcell.enterthemeeting.com/m/VVKE8XVK

Cost: Physicians & Medical Professionals can attend free – RSVP today

Kind Regards,

Dr. Dipnarine Maharaj

Medical Director

South Florida Bone Marrow/Stem Cell Transplant Institute

Related Links:

Physicians and Medical Professionals – Learn More About the Stem Cell Fellowship

Would you like to refer a patient to Dr. Maharaj?  Please use our patient referral form

Dr. Maharaj to Keynote at the CAM for Cancer Conference – See agenda here

To learn more about Dr. Maharaj, the physician’s network, or about the latest protocols for diseases like cancer, Parkinson’s, diabetes, and more please contact the office at:

 

International: (561) 752-5522

Email: info@bmscti.org

Copyright © 2014 South Florida Bone Marrow Stem Cell Transplant Institute, All rights reserved.

Dipnarine Maharaj Community Education Outreach Effort Begins

Community Education Outreach Effort Begins

Dipnarine Maharaj

Dr. Dipnarine Maharaj MD speaking at a lecture

 

As part of our ongoing efforts to promote the viability and efficacy of adult stem cells.  The Stem Cell Cancer and Regenerative Medicine Inc. Foundation has launched a new community outreach program designed to educate local groups in Palm Beach County and South Florida about the advances in adult stem cells as well as the approved treatable diseases.  In addition, we are also educating the community about our own clinical trial and what that could present to the future of Medicine for the treatment of illnesses such as Parkinson’s disease, diabetes, Alzheimer’s, and many others.

To date, the Foundation has coordinated adult stem cell lectures with the Rotary Club of Boca Raton Downtown, the Palm Beach County Democratic Club, Kiwanis Club of Boca Raton, Rotary Club of Delray Beach, Kiwanis Club of Palm Beach, Point Vecchio Community, Arden Courts Retirement Community, MDVIP Patient lecture series, Avenue Wellness Summer Lecture Series, and several other local synagogues and community groups.

Dr. Maharaj has been actively educating the general public on the need to collect and story their own stem cells while they are healthy so that they can have their immune systems stored in the event that they develop a major disease down the road.  As the number of approved indications rises the benefit of collecting and storing your stem cells will only grow.

Dr. Dipnarine Maharaj MD FACP – Welcome to My WordPress Site for Adult Stem Cells

Dr. Dipnarine Maharaj MD FACP – Welcome to My WordPress Site for Adult Stem Cells

 

WaddellsWhy bank adult stem cells?

In banking your own healthy adult stem cells, you will not need to depend on finding a matched donor.

1 in 200 people will need a stem cell transplant for a blood disorder during their lifetime. High dose chemotherapy followed by stem cell reinfusion has been the standard of care for many hematological disorders for decades. However, 70% of patients in need of a transplant do not have a matching donor or umbilical cord blood unit. (National Marrow Donor Registry, 2012). The best time to collect your adult stem cells is when you are healthy. A healthy immune system is the most important factor when it comes to longevity and the ability to fight off diseases. As you age, so do your stem cells, resulting in a steady decline in your stem cells’ efficacy, efficiency, and population. The time to collect and store your stem cells is NOW.

How can stem cells help you and your family

Although stem cell therapies currently only treat a few types of diseases due to the specialized nature of adult stem cells, the success of these established therapies, such as skin and blood transplants, provides hope that stem cells will be able to provide therapy for many diseases in the future that were previously thought to have no cure. Current treatment methods of many diseases involve simply alleviating symptoms, rather than curing the disease itself. Stem cells propose the possibility of re-growing the damaged cells, and then, being implanted in patients to replace damaged cells, ultimately curing the patient completely.

Blood and bone marrow stem cells, called hematopoietic cells, have been used for decades to treat leukemiassickle cell anemia, damaged bone marrow, and certain metabolic disorders and immunodeficiencies. Hematopoietic stem cells produce all types of blood cells, and preliminary tests have shown that these stem cells may also be able to give rise to other cell types besides blood cells.

The number of medical achievements stem cells have given rise to is growing at a rapid pace. Based on evolving research in regenerative medicine, we believe that the autologous (your own) stem cells will be used in the future to treat many diseases for which there are currently no cures. Having your stem cells collected today ensures that if they can be used to reverse any of these diseases you may develop, you are well prepared.